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CHICAGO Uomo Nike Shox OZ D Bianche Saldi , Nov. 7 (Xinhua) -- A study led by the University of Michigan (UM) found that increasing the levels of the fat hormone Neuregulin 4 (Nrg4) protected liver cells from metabolic stress in mice, while loss of the hormone had the opposite effect: mouse livers deteriorated and progressed to nonalcoholic steatohepatitis (NASH) more quickly.

UM cell biologist Jiandie Lin and his colleagues evaluated the effects of Nrg4 in mice that had been fed the type of high-fat, high-sugar diet that leads to fatty liver disease.

The findings have been published in the latest issue of the Journal of Clinical Investigation.

They found that when the hormone was elevated, less cell death Offerta Uomo Nike Shox OZ D Nere Rosse , less inflammation, less fibrosis were detected.

On the other hand, mice lacking the hormone fare much worse. The hormone is having a distinct function that limits cell death and prevents progression to the most severe fatty liver disease.

More than a third of U.S. adults and up to 10 percent of children have some form of fatty liver disease. In up to 20 percent of these patients, the liver cells begin dying Scontate Balenciaga Speed Trainer Knit High Runner Olive Bianche , and the disease develops into NASH.

It is estimated that by 2020, NASH will become the leading cause of the need for liver transplants, surpassing hepatitis and alcoholic liver disease.

The findings are an expansion of a previous study from Lin's lab, which showed Nrg4 could prevent the liver from converting sugar into fat Offerta Balenciaga Speed Trainer Knit High Runner Nere Bianche , lowering the risk of fatty liver disease at its outset.

Moreover, the researchers have not yet seen any negative side-effects in the mice with increased Nrg4.

Based on the findings, researchers believe that Nrg4 may be an effective target for therapeutic intervention of NASH.

Lin's lab is now focusing on further testing the therapeutic viability of the hormone in treating NASH.


JERUSALEM, Dec. 26 (Xinhua) -- A Qassam rocket was launched from the Gaza Strip into southern Israel on Thursday evening Air Max 90 Leather Nere Grigie Saldi , Israeli Police spokesperson Mickey Rosenfeld confirmed to Xinhua.

This is the second missile launched from the Hamas-ruled enclave unto southern Israel in the past 24 hours as another missile hit in an open territory in the Hof Ashkelon Regional Council on the night between Wednesday and Thursday.

An alert system was set off following the launch and the sound of explosion was heard. There were no reports of casualties or damages and police believes the missile also landed in an open area and is scanning the perimeters of the local council.

Earlier on Thursday, the Israeli military continued to boost up its preparedness for an escalation in the fighting with Palestinian militants in the strip and boosted the air-defense systems known as Iron Dome anti-missile batteries, to protect communities from future missile attacks.

According to the Walla! news website the batteries were deployed overnight in southern Israel, in the cities of Ashdod Uomo Air Max 90 Ultra Moire Nere Scontate , Be 'er Sheva and Ashkelon, following another battery stationed earlier on Wednesday near Sderot.

On Wednesday, Defense Minister Moshe Ya'alon said while visiting a military drill in the West Bank that the Israeli military is preparing for possible escalation in hostilities with Palestinian Militants.

His statements came a day after a Defense Ministry employer was killed by a Gaza sniper while fixing the border fence which was damaged from a recent storm.

""We practice, and at the same time our eyes are watching the different sectors and the Gaza Strip after the incident which occurred on Tuesday and ended in a disaster Scontate Air Max 97 OG UNDFTD Undefeated Militia Verdi Arancione ,"" Ya'alon said, the Walla news website reported.

""We're preparing for a possibility of an escalation; there is a deployment of Iron Dome batteries, including another one in Sderot, "" he added.

""We expect Hamas to impose its authority on its people. If it doesn't do so we will react as we did yesterday Acquistare Air Max 97 OG UNDFTD Undefeated Sail Bianche , in a strong manner,"" Ya'alon said, referring to the retaliatory Israeli Air Force raids in the strip on Tuesday following the deadly shooting, which resulted in the death of a 3 year-old girl and her father and several other injuries.

At least one Palestinian man was killed in the weekend while Palestinians who approached the fence were shot by Israeli soldiers. Other Palestinians hurled stones at a military post near the Gaza border.

A rocket was fired into Israel from the Gaza Strip overnight Sunday Donne Air Max 97 Shockproof Rosa Italia , hitting an open territory without injuries or damages reported.

There has been a relative calm between Israel and the Hamas-led Gaza Strip since its 8 days of fighting in November 2012, known as Operation Pillar of Defense.

According to Israeli security forces, the recent attacks may be caused by frustration due to the dire financial situation in the strip and the despair and conducted by small militant factions.

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BANGKOK, Nov. 2 (Xinhua) -- South Korea defeated China for the second time in one week to reach the final of 25th FIBA Asia Women 's Basketball Championship here on Saturday Acquistare Uomo Air Max 97 Bianche , while Japn beat Chinese Taipei for its first final after 2003.

Both Japan and South Korea qualified for the 2014 FIBA Women's Basketball World Championship which will be played in Turkey from September 27th to October 5th next year. China and Chinese Taipei will fight in the bronze medal match for the last ticket to Turkey.

Beon Yeon-Ha came up with her best game of the tournament for South Korea in their 71-66 semifinal victory against archrivals China, leading the team to their fifth successive Asian Championship final.

An incredible 9-of-17 field shooting, including a luminescent showing on the paint for 22 points and a limitless courtcraft that was reflected in the six assists she dished out spoke for Beon Yeon-Ha's contribution in the Korean success.

Chen Nan had a game-high 23 points and Gao Song 14 points. No other Chinese scored in the double-digit.

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